The QSAR, Molecular Modelling and Computational Chemistry research team is headed by Prof John Dearden, who is supported by Mark Cronin (expertise in toxicity prediction) and Dr Judith Madden (expertise in drug design and modelling of pharmacokinetic properties of drugs). The menu on the right of the screen provides information about the background to QSAR, current projects being undertaken, academic and research staff, and publications and consultancy.
The group will investigate the relationships between biological activity and the physico-chemical properties of compounds. This area will include the development of Quantitative Structure-Activity Relationships (QSARs) to predict pharmacological, toxicological and enzymic activity, as well as physico-chemical parameters. The researchers in QSAR are dedicated to application of these methods to industrial settings and the embedding of the science within the core teaching programs of the School of Pharmacy and Biomolecular Sciences at Liverpool John Moores University.