Dr Touraj Ehtezazi

Journal article

Ehtezazi T, Kteich A, Abdulkarim R, Anderson V, Algellay M, McCloskey AP, Carter N, Roberts M, Assi S, Al-Jumeily D, Thompson M, Mohamed FA, Sarker SD. 2024. Reducing temperature of fused deposition modelling 3D printing for linalool fast dissolving oral films by increasing printer nozzle diameter Journal of Pharmaceutical Sciences, DOI Author Url Publisher Url Public Url

Prieto JM, Fielding A, Ismail F, Nakouti I, Ehtezazi T, Rahman P, Fatokun AA, Ritchie KJ, Sarker SD. 2024. RESEARCH ACTIVITIES IN THE CENTRE FOR NATURAL PRODUCTS DISCOVERY IN 2023 Journal of Natural Products Discovery, 2 :1-6 DOI

Harland E, Alhusban D, Abdoubaki R, Marfing D, Simm A, McCloskey AP, Ehtezazi T, Ross K. 2023. A novel peptide for microRNA delivery to medulloblastoma cells Biomolecular Research Reports, 1 :1-11 Publisher Url Public Url

Ehtezazi T, Kteich A, Abdulkarim R, Lynch R, Algellay M, McCloskey AP, Roberts M, Sarker SD. 2023. Quantification of Linalool in 3D Printed Fast-Dissolving Oral Films by A High-Pressure Liquid Chromatography Method Journal of Natural Products Discovery, 2 :1-9 DOI Publisher Url Public Url

McCloskey AP, Bracken L, Vasey N, Ehtezazi T. 2023. 3D printing–an alternative strategy for pediatric medicines Expert Review of Clinical Pharmacology, 16 :613-616 DOI Author Url Publisher Url

Ehtezazi T, Rahman K, Davies R, Leach AG. 2023. The Pathological Effects of Circulating Hydrophobic Bile Acids in Alzheimer's Disease. Journal of Alzheimer's disease reports, 7 :173-211 DOI Author Url Publisher Url Public Url

Algellay M, Roberts M, Bosworth L, Sarker S, Fatokun AA, Ehtezazi T. 2023. The Use of Micro-Ribbons and Micro-Fibres in the Formulation of 3D Printed Fast Dissolving Oral Films Pharmaceuticals, 16 DOI Author Url Publisher Url Public Url

Ehtezazi T, Sarker SD. 2022. The Use of natural Products in 3D Printing of Pharmaceutical Dosage Forms Journal of Natural Products Discovery, 1 DOI Publisher Url Public Url

Ehtezazi T. 2021. The Potential Use of Cyclosporine Ultrafine Solution Pressurised Metered-Dose Inhaler in the Treatment of COVID-19 Patients Recent Advances in Drug Delivery and Formulation, 15 :1-13 DOI Author Url Publisher Url Public Url

Islam Y, Leach AG, Smith J, Pluchino S, Coxon CR, Sivakumaran M, Downing J, Fatokun AA, Teixidò M, Ehtezazi T. 2021. Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles Advanced Science, DOI Author Url Publisher Url Public Url

Ehtezazi T, Evans DG, Jenkinson ID, Evans PA, Vadgama VJ, Vadgama J, Jarad F, Grey N, Chilcott RP. 2021. SARS-CoV-2: characterisation and mitigation of risks associated with aerosol generating procedures in dental practices. British Dental Journal (BDJ), DOI Author Url Publisher Url Public Url

Islam Y, Ehtezazi P, Cashmore A, Marinsalda E, Leach AG, Coxon CR, Fatokun AA, Sexton DW, Khan I, Zouganelis GD, Downing J, Pluchino S, Sivakumaran M, Teixido M, Ehtezazi T. 2020. The Inclusion of a Matrix Metalloproteinase-9 Responsive Sequence in Self-assembled Peptide-based Brain-Targeting Nanoparticles Improves the Efficiency of Nanoparticles Crossing the Blood-Brain Barrier at Elevated MMP-9 Levels Journal of Pharmaceutical Sciences, 110 :1349-1364 DOI Author Url Publisher Url Public Url

Islam Y, Khalid A, Pluchino S, Sivakumaran M, Teixidò M, Leach AG, Fatokun AA, Downing J, Coxon CR, Ehtezazi T. 2020. Development of Brain Targeting Peptide Based MMP-9 Inhibiting Nanoparticles for the Treatment of Brain Diseases with Elevated MMP-9 Activity. Journal of Pharmaceutical Sciences, 109 :3134-3144 DOI Author Url Publisher Url Public Url

Islam Y, Leach AG, Smith J, Pluchino S, Coxon CR, Sivakumaran M, Downing J, Fatokun AA, Teixidò M, Ehtezazi T. 2020. Peptide based drug delivery systems to the brain Nano Express, DOI Publisher Url Public Url

Bnyan R, Cesarini L, Khan I, Roberts M, Ehtezazi T. 2020. The Effect of Ethanol Evaporation on the Properties of Inkjet Produced Liposomes DARU : Journal of Pharmaceutical Sciences, 28 :271-280 DOI Author Url Publisher Url Public Url

Ehtezazi T, Algellay M, Hardy A. 2019. Next steps in 3D Printing of Fast Dissolving oral Films for Commercial Production. Recent Patents on Drug Delivery and Formulation, DOI Author Url Publisher Url Public Url

Bnyan R, Khan I, Ehtezazi T, Saleem IY, Gordon S, O'Neill F, Roberts M. 2019. Formulation and optimisation of novel transfersomes for sustained release of local anaesthetic Journal of Pharmacy and Pharmacology, DOI Author Url Publisher Url Public Url

Bnyan R, Khan I, Ehtezazi T, Saleem I, Gordon S, Neill FO, Roberts M. 2018. Surfactant effects on lipid-based vesicles properties. Journal of Pharmaceutical Sciences, DOI Author Url Publisher Url Public Url

Ehtezazi T, Algellay M, Islam Y, Roberts M, Dempster NM, Sarker SD. 2017. The Application of 3D Printing in the Formulation of Multilayered Fast Dissolving Oral Films. Journal of Pharmaceutical Sciences, 107 :1076-1085 DOI Author Url Publisher Url Public Url

Ehtezazi T, Davies MJ, Seton L, Morgan MN, Ross S, Martin GD, Hutchings IM. 2015. Optimizing the primary particle size distributions of pressurized metered dose inhalers by using inkjet spray drying for targeting desired regions of the lungs. Drug Dev Ind Pharm, 41 :279-291 DOI Author Url Publisher Url Public Url

Ehtezazi T, Dempster NM, Martin GD, Hoath SD, Hutchings IM. 2014. Development of High-Throughput Glass Inkjet Devices for Pharmaceutical Applications JOURNAL OF PHARMACEUTICAL SCIENCES, 103 :3733-3742 DOI Author Url Publisher Url Public Url

Ehtezazi T, Dempster NM, Martin GD, Hoath SD, Hutchings IM. 2014. Development of high-throughput glass inkjet devices for pharmaceutical applications Journal of Pharmaceutical Sciences, 103 :3733-3742 DOI

Jones RW, Chaudary S, Ehtezazi T, Sheikh M. 2014. Review of Core Principles and Best Practice in the Teaching of Aseptic Manufacturing in UK Schools of Pharmacy European Journal of Parenteral and Pharmaceutical Sciences, 19 :170-179 Publisher Url Public Url

Ehtezazi T, Turner MA. 2013. The application of mechanical aerosol delivery systems in an in vitro model of mechanically ventilated neonates. Recent Pat Drug Deliv Formul, 7 :174-183 DOI Author Url Publisher Url

Ehtezazi T. 2012. Recent patents in pressurised metered dose inhalers. Recent Pat Drug Deliv Formul, 6 :31-44 DOI Author Url Publisher Url

Roberts M, Ehtezazi T, Compernolle A, Amin K. 2011. The effect of spray drying on the compaction properties of hypromellose acetate succinate. Drug Dev Ind Pharm, 37 :268-273 DOI Author Url Publisher Url

Ehtezazi T, Saleem I, Shrubb I, Allanson DR, Jenkinson ID, O'Callaghan C. 2010. The interaction between the oropharyngeal geometry and aerosols via pressurised metered dose inhalers. Pharm Res, 27 :175-186 DOI Author Url Publisher Url

Ehtezazi T, Allanson DR, Jenkinson ID, Shrubb I, O'Callaghan C. 2008. Investigating improving powder deagglomeration via dry powder inhalers at a low inspiratory flow rate by employing add-on spacers. J Pharm Sci, 97 :5212-5221 DOI Author Url Publisher Url

Ehtezazi T, Allanson DR, Jenkinson ID, O'Callaghan C. 2006. Effect of oropharyngeal length in drug lung delivery via suspension pressurized metered dose inhalers. Pharm Res, 23 :1364-1372 DOI Author Url Publisher Url

Ehtezazi T, Kodjaian K, Larhrib H. 2005. Use of corrugated gelatin particles in dry powder inhalation aerosols JOURNAL OF PHARMACY AND PHARMACOLOGY, 57 :S86-S87 Author Url

Patel J, Ehtezazi T, Dyas AM, Riby P, Larhrib H. 2005. Dextran as a carrier for dry powder inhalation formulations JOURNAL OF PHARMACY AND PHARMACOLOGY, 57 :S96-S96 Author Url

Ehtezazi T, Horsfield MA, Barry PW, Goodenough P, O'callaghan C. 2005. Effect of device inhalational resistance on the three-dimensional configuration of the upper airway. J Pharm Sci, 94 :1418-1426 DOI Author Url Publisher Url

Ehtezazi T, Southern KW, Allanson D, Jenkinson I, O'Callaghan C. 2005. Suitability of the upper airway models obtained from MRI studies in simulating drug lung deposition from inhalers. Pharm Res, 22 :166-170 DOI Author Url Publisher Url

Ehtezazi T, Horsfield MA, Barry PW, O'Callaghan C. 2004. Dynamic change of the upper airway during inhalation via aerosol delivery devices. J Aerosol Med, 17 :325-334 DOI Author Url Publisher Url

Ehtezazi T, Rungsardthong U, Stolnik S. 2003. Thermodynamic analysis of polycation-DNA interaction applying titration microcalorimetry LANGMUIR, 19 :9387-9394 DOI Author Url Publisher Url

Rungsardthong U, Ehtezazi T, Bailey L, Armes SP, Garnett MC, Stolnik S. 2003. Effect of polymer ionization on the interaction with DNA in nonviral gene delivery systems. Biomacromolecules, 4 :683-690 DOI Author Url Publisher Url

Ehtezazi T, Washington C. 2000. Controlled release of macromolecules from PLA microspheres: using porous structure topology. J Control Release, 68 :361-372 DOI Author Url Publisher Url

Ehtezazi T, Govender T, Stolnik S. 2000. Hydrogen bonding and electrostatic interaction contributions to the interaction of a cationic drug with polyaspartic acid. Pharm Res, 17 :871-878 DOI Author Url Publisher Url

Ehtezazi T, Washington C, Melia CD. 2000. First order release rate from porous PLA microspheres with limited exit holes on the exterior surface. J Control Release, 66 :27-38 DOI Author Url Publisher Url

Govender T, Riley T, Ehtezazi T, Garnett MC, Stolnik S, Illum L, Davis SS. 2000. Defining the drug incorporation properties of PLA-PEG nanoparticles. Int J Pharm, 199 :95-110 DOI Author Url Publisher Url

Govender T, Ehtezazi T, Stolnik S, Illum L, Davis SS. 1999. Complex formation between the anionic polymer (PAA) and a cationic drug (procaine HCI): characterization by microcalorimetric studies. Pharm Res, 16 :1125-1131 DOI Author Url Publisher Url

Ehtezazi T, Washington C, Melia CD. 1999. Determination of the internal morphology of poly (D,L-lactide) microspheres using stereological methods. J Control Release, 57 :301-314 DOI Author Url Publisher Url

Ehtezazi T, Melia CD, Washington C. 1997. Obtaining pore size distributions within porous microspheres using stereological methods Proceedings of the Controlled Release Society, :629-630

Ghassabian S, Ehtezazi T, Forutan SM, Mortazavi SA. 1996. Dexamethasone-loaded magnetic albumin microspheres: Preparation and in vitro release INTERNATIONAL JOURNAL OF PHARMACEUTICS, 130 :49-55 DOI Author Url Publisher Url

Conference publication

Ehtezazi T, Kelly N, McCloskey A, Sarker S. 2023. USE OF NATURAL PRODUCTS IN 3D PRINTING OF MEDICINAL TEDDY BEARS Journal of Natural Products Discovery, 4th Annual CNPD (Centre for Natural Products Discovery) Conference 2 :7-7 DOI

Thompson M, Assi S, Obe DAJ, McCloskey AP, Sarker SD, Tang L, Mohamed FA, Wilson M, Ehtezazi T. 2023. Use of Raman and Fourier Transform Infrared Spectroscopy as a Quality Control of 3D printed Linalool Fast Dissolving Oral Films Proceedings - International Conference on Developments in eSystems Engineering, DeSE, :498-503 DOI Publisher Url

Islam Y, Leach AG, Coxon CR, Downing J, Platt M, Pluchino S, Ehtezazi T. 2017. Smart micellar systems for brain drug delivery KTN Biopharmaceutical Formulation Group Public Url

Sindu S, Ehtezazi T. 2003. Reformulation of magnesium sulphate paste BPC

Ehtezazi T, Govender T, Jenssen D, Stolnik S, Davis SS. 1999. The role of hydrogen binding in complex formation between cationic drugs and poly (aspartic acid) Proceedings of the Controlled Release Society, :659-660

Ehtezazi T, Washington C, Melia CD. 1999. Effect of thickening agents in porous PLA microspheres on the release of macromolecules Proceedings of the Controlled Release Society, :685-686

Ehtezazi T, Washington C, Melia CD. 1998. Limited surface access of porous PLA microspheres Proceedings of the Controlled Release Society, :707-708

Islam Y, Leach A, Downing J, Fatokun A, Sexton D, Coxon CR, Zouganelis G, Pluchino S, Sivakumran M, Teixido M, Ehtezazi T. MMP-9-responsive self-assembled nanocarriers for brain drug delivery Keele Nanoparticle Conference

Editorial/letter to the editor

Ehtezazi T. 2023. Special Issue for “3D Printing of Drug Formulations” Pharmaceuticals, 16 :1372 DOI Author Url Publisher Url

Chapters

Ehtezazi T. 2023. The Application of 3D Print in the Formulation of Novel Pharmaceutical Dosage Forms 3D Printing: Fundamentals to Emerging Applications :403-418 DOI Publisher Url

Hugo WB, Denyer SP, Hodges NA, Gorman SP, Ford JL. 2004. Hugo and Russell's pharmaceutical microbiology :323-345 Wiley-Blackwell 9780632064670

Other

Ehtezazi T. 2021. Correction to: SARS-CoV-2: characterisation and mitigation of risks associated with aerosol generating procedures in dental practices (Feb, 10.1038/s41415-020-2504-8, 2021) BRITISH DENTAL JOURNAL, DOI Author Url Publisher Url

Ehtezazi T. 2018. Smart Nanocarriers for Drug Delivery to the Brain

preprint

Ehtezazi T, Evans DG, Jenkinson ID, Evans P, Vadgama VJ, Vadgama J, Jarad F, Grey N, Chilcott RP. 2020. SARS-CoV-2: Characterisation and Mitigation of Risks Associated with Aerosol Generating Procedures (AGPs) in Dental Practices Research Square Platform LLC DOI Publisher Url

Poster

Islam Y, Leach A, Downing J, Fatokun AA, Sexton D, Coxon CR, Zouganelis G, Pluchino S, Sivakumran M, Teixido M, Ehtezazi T. 2019. MMP-9-responsive self-assembled nanocarriers for brain drug delivery Keele Nanoparticle Conference, Keele University, UK. 5 July, 2019.

Bnyan R, Khan I, Ehtezazi T, Saleem I, Gordon S, O’Neill, F, Roberts M. 2019. A novel carrier system via deformable liposomes using local anaesthetic for buccal delivery PharmSci conference Greenwich, UK

Ehtezazi T, Turner M, Alzoubi T. 2010. An in Vitro Model to Simulate More Realistic Aerosol Lung Deposition in Mechanically Ventilated Neonates. Drug Delivery to the Lungs XXI

Ehtezazi T, Turner M. 2009. Reducing the Amount of Alcohol Delivered to Neonates via Pressurised Metered Dose Inhalers Containing Alcohol. Drug Delivery to the Lungs XX, London, Dec 2009

Ehtezazi T, Horsfield MA, Barry PW, O’Callaghan C. 2001. Smoothing the stepwise structure of the upper airway reconstructed from the rapid MR scans. Drug Delivery to the Lungs. 2001, XII

Harrington L, Versteed HK, Ehtezazi T, O’Callaghan C, Barry PW, Horsfield MA. 2001. Comparison of the development of a pharmaceutical aerosol in USP and “biological” throats using computational fluid dynamics.

Ehtezazi T, Horsfield MA, Barry PW, O’Callaghan C. 2000. 3D Reconstruction of the Upper Airway During Inhalation from Drug Delivery Systems. DDL, London, Dec, 2001

Ehtezazi T, Melia CD, Washington C. 1997. Using Stereological Methods to Determine the Pore Size Distribution of Microspheres The 24th International Symposium on Controlled Release of Bioactive Materials : proceedings 1997 : Stockholmsmässan, Stockholm, Sweden, June 15-19, 1997

Other Professional Activity:

Lead Supervisor For an MPhil project. The student is Ayub Khan. 2021

Editorial boards:

Pharmaceuticals, Guest Executive Editor. 2020

Award:

Illuminating wound closure: 3D-printed fast-dissolving polymer films for light-triggered tissue repair, Newton International Fellowships. 2018

Developing novel pressurised metered dose inhalers, Coster (Italy). 2008

Immobilisation of rhDNase on biodegradable microspheres, GenenTech. 2007

Research Grants Awarded:

3M Healthcare, Development of inkjet spray drying for inhalers., Grant value (£): 60,000, Duration of research project: 36 month. 2010

Janssen Pharmaceutical NV, Beerse, Belgium, The effects of spray drying on the compaction properties of hypromellose acetate succinate, Dr Matt-Roberts, Grant value (£): £17,400. 2008

Novartis Vaccines, Optimising aseptic procedures, Profesdsor James Ford, Grant value (£): £114,750, Duration of research project: 12 month. 2006

AstraZeneca foundations, The Effect of the Upper Airway on the Deposition of Inhaled Medication, Prfessor Christopher O'Callaghan, Grant value (£): £20,000, Duration of research project: 12 Month. 2001