Journal article
Norman BP, Sutherland H, Wilson PJM, Rutland DA, Milan AM, Hughes AT, Davison AS, Khedr M, Jarvis JC, Gallagher JA, Bou-Gharios G, Ranganath LR. 2024. Hepatobiliary circulation and dominant urinary excretion of homogentisic acid in a mouse model of alkaptonuria Journal of Inherited Metabolic Disease, DOI Author Url Publisher Url Public Url
Viggars MR, Sutherland H, Cardozo CP, Jarvis JC. 2023. Conserved and species-specific transcriptional responses to daily programmed resistance exercise in rat and mouse The FASEB Journal, 37 :1-20 DOI Author Url Publisher Url Public Url
Viggars MR, Sutherland H, Lanmüller H, Schmoll M, Bijak M, Jarvis JC. 2022. Adaptation of the transcriptional response to resistance exercise over 4 weeks of daily training FASEB Journal, 37 DOI Author Url Publisher Url Public Url
Norman BP, Davison AS, Hickton B, Ross GA, Milan AM, Hughes AT, Wilson PJM, Sutherland H, Hughes JH, Roberts NB, Bou-Gharios G, Gallagher JA, Ranganath LR. 2022. Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria Metabolites, 12 DOI Author Url Publisher Url Public Url
Davison AS, Norman BP, Sutherland H, Milan AM, Gallagher JA, Jarvis JC, Ranganath LR. 2022. Impact of Nitisinone on the Cerebrospinal Fluid Metabolome of a Murine Model of Alkaptonuria Metabolites, 12 DOI Author Url Publisher Url Public Url
Norman BP, Davison AS, Hughes JH, Sutherland H, Wilson PJ, Berry NG, Hughes AT, Milan AM, Jarvis JC, Roberts NB, Ranganath LR, Bou-Gharios G, Gallagher JA. 2021. Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism Genes and Diseases, 9 :1129-1142 DOI Author Url Publisher Url Public Url
Hughes JH, Keenan CM, Sutherland H, Edwards HR, Wilson PJM, Ranganath LR, Jarvis JC, Bou-Gharios G, Gallagher JA. 2020. Anatomical Distribution of Ochronotic Pigment in Alkaptonuric Mice is Associated with Calcified Cartilage Chondrocytes at Osteochondral Interfaces Calcified Tissue International, DOI Author Url Publisher Url Public Url
Hesketh SJ, Sutherland H, Lisboa PJ, Jarvis JC, Burniston JG. 2020. Adaptation of rat fast-twitch muscle to endurance activity is underpinned by changes to protein degradation as well as protein synthesis. FASEB Journal, DOI Author Url Publisher Url Public Url
Stead CA, Hesketh SJ, Bennett S, Sutherland H, Jarvis JC, Lisboa PJ, Burniston JG. 2020. Fractional Synthesis Rates of Individual Proteins in Rat Soleus and Plantaris Muscles. Proteomes, 8 DOI Author Url Publisher Url Public Url
Khedr M, Cooper MS, Hughes AT, Milan AM, Davison AS, Norman BP, Sutherland H, Jarvis JC, Fitzgerald R, Markinson L, Psarelli E-E, Ghane P, Deutz NEP, Gallagher JA, Ranganath LR. 2020. Nitisinone causes acquired tyrosinosis in alkaptonuria. Journal of Inherited Metabolic Diseases, DOI Author Url Publisher Url Public Url
Hughes JH, Wilson PJM, Sutherland H, Judd S, Hughes AT, Milan AM, Jarvis JC, Bou-Gharios G, Ranganath LR, Gallagher JA. 2020. Dietary restriction of tyrosine and phenylalanine lowers tyrosinaemia associated with nitisinone therapy of alkaptonuria. Journal of Inherited Metabolic Disease, :1-10 DOI Author Url Publisher Url Public Url
Hughes JH, Liu K, Plagge A, Wilson PJM, Sutherland H, Norman BP, Hughes AT, Keenan CM, Milan AM, Sakai T, Ranganath LR, Gallagher JA, Bou-Gharios G. 2019. Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria HUMAN MOLECULAR GENETICS, 28 :3928-3939 DOI Author Url Publisher Url
Keenan CM, Beckett AJ, Sutherland H, Ranganath LR, Jarvis JC, Prior IA, Gallagher JA. 2019. Concentric lamellae - novel microanatomical structures in the articular calcified cartilage of mice SCIENTIFIC REPORTS, 9 DOI Author Url Publisher Url Public Url
Seaborne RA, Hughes DC, Turner DC, Owens DJ, Baehr LM, Gorski P, Semenova EA, Borisov OV, Larin AK, Popov DV, Generozov EV, Sutherland H, Ahmetov II, Jarvis JC, Bodine SC, Sharples AP. 2019. UBR5 is a Novel E3 Ubiquitin Ligase involved in Skeletal Muscle Hypertrophy and Recovery from Atrophy The Journal of Physiology, DOI Author Url Publisher Url Public Url
Davison AS, Strittmatter N, Sutherland H, Hughes AT, Hughes J, Bou-Gharios G, Milan AM, Goodwin RJA, Ranganath LR, Gallagher JA. 2019. Correction to: Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging. Metabolomics : Official journal of the Metabolomic Society, 15 :81 DOI Author Url Publisher Url
Norman BP, Davison AS, Ross GA, Milan AM, Hughes AT, Sutherland H, Jarvis JC, Roberts NB, Gallagher JA, Ranganath LR. 2019. A Comprehensive LC-QTOF-MS Metabolic Phenotyping Strategy: Application to Alkaptonuria CLINICAL CHEMISTRY, 65 :530-539 DOI Author Url Publisher Url
Davison AS, Strittmatter N, Sutherland H, Hughes AT, Hughes J, Bou-Gharios G, Milan AM, Goodwin RJA, Ranganath LR, Gallagher JA. 2019. Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging. Metabolomics : Official journal of the Metabolomic Society, 15 :68 DOI Author Url Publisher Url
Schmoll M, Unger E, Sutherland H, Haller M, Bijak M, Lanmueller H, Jarvis JC. 2018. SpillOver stimulation: A novel hypertrophy model using co-contraction of the plantar-flexors to load the tibial anterior muscle in rats PLOS ONE, 13 DOI Author Url Publisher Url Public Url
Hughes JH, Liu K, Sutherland H, Wilson PJ, Hughes AT, Milan AM, Ranganath LR, Gallagher JA, Bou-Gharios G. 2018. Generation and phenotyping of a targeted mouse model of alkaptonuria Osteoarthritis and Cartilage, 26 :S89-S90 DOI Publisher Url
Norman BP, Ying CW, Sutherland H, Wilson PJ, Roberts NB, Duer MJ, Oschkinat H, Ranganath LR, Gallagher JA. 2018. Disruption of collagen triple helix hydrogen bonding in ochronotic human cartilage in alkaptonuria observed by dynamic nuclear polarisation-enhanced solid-state nuclear magnetic resonance spectroscopy Osteoarthritis and Cartilage, 26 :S99-S99 DOI Publisher Url
Schmoll M, Unger E, Sutherland H, Haller M, Bijak M, Lanmüller H, Jarvis JC. 2017. In-situ measurements of tensile forces in the tibialis anterior tendon of the rat in concentric, isometric, and resisted co-contractions. Physiological Reports, 5 DOI Author Url Publisher Url Public Url
Hesketh SJ, Srisawat K, Sutherland H, Jarvis JC, Burniston JG. 2016. On the Rate of Synthesis of Individual Proteins within and between Different Striated Muscles of the Rat Proteomes, 4 :1-15 DOI Author Url Publisher Url Public Url
Keenan CM, Preston AJ, Sutherland H, Wilson PJ, Psarelli EE, Cox TF, Ranganath LR, Jarvis JC, Gallagher JA. 2015. Nitisinone Arrests but Does Not Reverse Ochronosis in Alkaptonuric Mice. JIMD Reports, 24 :45-50 DOI Author Url Publisher Url Public Url
Vickerton P, Jarvis JC, Gallagher JA, Akhtar R, Sutherland H, Jeffery N. 2014. Morphological and histological adaptation of muscle and bone to loading induced by repetitive activation of muscle PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 281 DOI Author Url Publisher Url
Keenan CM, Beckett A, Sutherland H, Prior I, Ranganath LR, Jarvis JC, Gallagher JA. 2014. IDENTIFICATION OF CONCENTRIC LAMELLAE IN THE ARTICULAR CALCIFIED CARTILAGE OF OSTEOARTHRITIC MICE OSTEOARTHRITIS AND CARTILAGE, 22 :S363-S364 DOI Author Url Publisher Url
Keenan CM, Sutherland H, Ranganath LR, Jarvis JC, Gallagher JA. 2014. 192. Development of Osteoarthritis in Alkaptonuric Mice Rheumatology, 53 :i131-i131 DOI Publisher Url
Preston AJ, Keenan CM, Sutherland H, Wilson PJ, Wlodarski B, Taylor AM, Williams DP, Ranganath LR, Gallagher JA, Jarvis JC. 2014. Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone ANNALS OF THE RHEUMATIC DISEASES, 73 :284-289 DOI Author Url Publisher Url
Keenan CM, Preston AJ, Sutherland H, Taylor AM, Wilson PJ, Williams D, Ranganath LR, Gallagher JA, Jarvis JC. 2013. Initiation and progression of ochronotic osteoarthropathy in alkaptonuric mice Osteoarthritis and Cartilage, 21 :S70-S71 DOI Publisher Url
Taylor AM, Preston AJ, Paulk NK, Sutherland H, Keenan CM, Wilson PJM, Wlodarski B, Grompe M, Ranganath LR, Gallagher JA, Jarvis JC. 2012. Ochronosis in a murine model of alkaptonuria is synonymous to that in the human condition OSTEOARTHRITIS AND CARTILAGE, 20 :880-886 DOI Author Url Publisher Url
Salmons S, Russold M, Ramnarine I, Ashley Z, Sutherland H, Jarvis J. 2010. Can you make a sphincter out of skeletal muscle? Physiology News, :23-25 DOI Publisher Url
Russold MF, Ramnarine I, Ashley Z, Sutherland H, Salmons S, Jarvis JC. 2010. Practical and Effective Stomal Sphincter Creation: Evaluation in Pigs DISEASES OF THE COLON & RECTUM, 53 :467-474 DOI Author Url Publisher Url
Ashley Z, Sutherland H, Russold MF, Lanmueller H, Mayr W, Jarvis JC, Salmons S. 2008. Therapeutic stimulation of denervated muscles: The influence of pattern MUSCLE & NERVE, 38 :875-886 DOI Author Url Publisher Url
Ashley Z, Salmons S, Boncompagni S, Protasi F, Russold M, Lanmuller H, Mayr W, Sutherland H, Jarvis JC. 2007. Effects of chronic electrical stimulation on long-term denervated muscles of the rabbit hind limb JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 28 :203-217 DOI Author Url Publisher Url
Ashley Z, Sutherland H, Lanmueller H, Russold MF, Unger E, Bijak M, Mayr W, Boncompagni S, Protasi F, Salmons S, Jarvis JC. 2007. Atrophy, but not necrosis, in rabbit skeletal muscle denervated for periods up to one year AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 292 :C440-C451 DOI Author Url Publisher Url
Sutherland H, Salmons S, Ramnarine IR, Capoccia M, Walsh AA, Jarvis JC. 2006. Adaptive conditioning of skeletal muscle in a large animal model (Sus domesticus) JOURNAL OF ANATOMY, 209 :165-177 DOI Author Url Publisher Url
Ramnarine IR, Capoccia M, Ashley Z, Sutherland H, Russold M, Summerfield N, Salmons S, Jarvis JC. 2006. Counterpulsation from the skeletal muscle ventricle and the intraaortic balloon pump in the normal and failing circulations CIRCULATION, 114 :I10-I15 DOI Author Url Publisher Url
Ramnarine IR, Capoccia M, Ashley Z, Sutherland H, Russold M, Summerfield N, Salmons S, Jarvis JC. 2006. Counterpulsation from the skeletal muscle ventricle and the intraaortic balloon pump in the normal and failing circulations Circulation, 114 DOI
Lanmuller H, Ashley Z, Unger E, Sutherland H, Reichel M, Russold M, Jarvis J, Mayr W, Salmons S. 2005. Implantable device for long-term electrical stimulation of denervated muscles in rabbits MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 43 :535-540 DOI Author Url Publisher Url
Salmons S, Ashley Z, Sutherland H, Russold MF, Li F, Jarvis JC. 2005. Functional electrical stimulation of denervated muscles: Basic issues ARTIFICIAL ORGANS, 29 :199-202 DOI Author Url Publisher Url
Ashley Z, Sutherland H, Lanmuller H, Unger E, Li F, Mayr W, Kern H, Jarvis JC, Salmons S. 2005. Determination of the chronaxie and rheobase of denervated limb muscles in conscious rabbits ARTIFICIAL ORGANS, 29 :212-215 DOI Author Url Publisher Url
Sutherland H, Zolle O, Khundkar R, Simpson AWM, Jarvis JC, Salmons S. 2004. A nonradioactive assay for nitric oxide synthase activity in tissue extracts. Methods in molecular biology (Clifton, N.J.), 279 :105-111 DOI Author Url Publisher Url
Sutherland H, Jarvis JC, Salmons S. 2003. Pattern dependence in the stimulation-induced type transformation of rabbit fast skeletal muscle NEUROMODULATION, 6 :176-189 DOI Author Url Publisher Url
Capoccia M, Sutherland H, Salmons S, Jarvis JC. 2002. The Hemodynamic function of intrathoracic skeletal muscle ventricles after recovery from surgery in pigs ARTIFICIAL ORGANS, 26 :235-237 DOI Author Url Publisher Url
Sutherland H, Khundkar R, Zolle O, McArdle A, Simpson AWM, Jarvis JC, Salmons S. 2001. A fluorescence-based method for measuring nitric oxide in extracts of skeletal muscle NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 5 :475-481 DOI Author Url Publisher Url
Lopez-Guajardo A, Sutherland H, Jarvis JC, Salmons S. 2001. Induction of a fatigue-resistant phenotype in rabbit fast muscle by small daily amounts of stimulation JOURNAL OF APPLIED PHYSIOLOGY, 90 :1909-1918 DOI Author Url Publisher Url
Lopez-Guajardo A, Sutherland H, Jarvis JC, Salmons S. 2000. Dynamics of stimulation-induced muscle adaptation: insights from varying the duty cycle JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 21 :725-735 DOI Author Url Publisher Url
Sutherland H, Jarvis JC, Kwende MMN, Gilroy SJ, Salmons S. 1998. The dose-related response of rabbit fast muscle to long-term low-frequency stimulation MUSCLE & NERVE, 21 :1632-1646 DOI Author Url Publisher Url
Salmons S, Tang ATM, Sutherland H, Jarvis JC. 1998. Long-term plasticity of motor unit properties and its application in man JOURNAL OF PHYSIOLOGY-LONDON, 506P :7S-7S Author Url
Jones J, Emmanuel J, Sutherland H, Jackson MJ, Jarvis JC, Salmons S. 1997. Stimulation-induced skeletal muscle damage: Cytoprotective effect of prestimulation BASIC AND APPLIED MYOLOGY, 7 :39-44 Author Url
Jarvis JC, Mokrusch T, Kwende MMN, Sutherland H, Salmons S. 1996. Fast-to-slow transformation in stimulated rat muscle MUSCLE & NERVE, 19 :1469-1475 DOI Author Url Publisher Url
Salmons S, Jarvis JC, Sutherland H, Gilroy SJ, Kwende MMN. 1996. Optimizing the properties of functional skeletal muscle grafts JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 17 :97-97 Author Url
Jarvis JC, Sutherland H, Mayne CN, Gilroy SJ, Salmons S. 1996. Induction of a fast-oxidative phenotype by chronic muscle stimulation: Mechanical and biochemical studies American Journal of Physiology - Cell Physiology, 270 DOI Author Url Publisher Url
Mayne CN, Sutherland H, Jarvis JC, Gilroy SJ, Craven AJ, Salmons S. 1996. Induction of a fast-oxidative phenotype by chronic muscle stimulation: histochemical and metabolic studies. The American journal of physiology, 270 :C313-C320 DOI Author Url Publisher Url
Mayne CN, Sutherland H, Jarvis JC, Gilroy SJ, Craven AJ, Salmons S. 1996. Induction of a fast-oxidative phenotype by chronic muscle stimulation: Histochemical and metabolic studies American Journal of Physiology - Cell Physiology, 270 DOI
Jarvis JC, Sutherland H, Mayne CN, Gilroy SJ, Salmons S. 1996. Induction of a fast-oxidative phenotype by chronic muscle stimulation: Mechanical and biochemical studies AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 270 :C306-C312 DOI Author Url
Mayne CN, Sutherland H, Jarvis JC, Gilroy SJ, Craven AJ, Salmons S. 1996. Induction of a fast-oxidative phenotype by chronic muscle stimulation: Histochemical and metabolic studies AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 270 :C313-C320 DOI Author Url
JARVIS JC, SUTHERLAND H, KWENDE MMN, GILROY S, SALMONS S. 1994. TO WHAT EXTENT CAN WE ENGINEER THE PROPERTIES OF SKELETAL-MUSCLE FOR CARDIAC ASSISTANCE JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 15 :178-178 Author Url
JARVIS JC, MAYNE CN, LITTLE P, SUTHERLAND H, BROWNSON C, SALMONS S. 1993. USE OF 2.5 HZ AND 10 HZ STIMULATION TO EXAMINE COORDINATION IN THE PHENOTYPIC RESPONSE OF FAST SKELETAL-MUSCLE TO INCREASED USE (VOL 13, P 237, 1991) JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 14 :279-279 Author Url
JARVIS JC, MOKRUSCH T, MAYNE CN, KWENDE MMN, GILROY S, SUTHERLAND H, SALMONS S. 1993. FAST-TO-SLOW FIBER-TYPE CONVERSION DOES OCCUR IN CONTINUOUSLY STIMULATED RAT HINDLIMB MUSCLE JOURNAL OF PHYSIOLOGY-LONDON, 467 :P112-P112 Author Url
JARVIS JC, SUTHERLAND H, SALMONS S. 1991. THE EFFECT OF CHRONIC ELECTRICAL-STIMULATION ON THE SPEED, POWER OUTPUT AND FATIGUE RESISTANCE OF FAST TWITCH SKELETAL-MUSCLE JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 12 :80-81 Author Url
preprint
Norman BP, Sutherland H, Wilson PJM, Rutland DA, Milan AM, Hughes AT, Davison AS, Khedr M, Jarvis JC, Gallagher JA, Bou-Gharios G, Ranganath LR. 2023. Bile is a route of excretion for homogentisic acid in alkaptonuria Cold Spring Harbor Laboratory DOI Publisher Url
Viggars MR, Sutherland H, Cardozo CP, Jarvis JC. 2023. Conserved and species-specific transcriptional responses to daily programmed resistance exercise in rat and mouse Cold Spring Harbor Laboratory DOI Publisher Url
Alhashmi M, Gremida AME, Al-Maslamani NA, Liu K, Sutherland H, Wilson P, Clegg P, van ’t Hof RJ, Bou-Gharios G, Yamamoto K. 2023. Skeletal progenitor LRP1-mediated endocytosis is critical for synovial joint formation and bone growth Cold Spring Harbor Laboratory DOI Publisher Url
Norman BP, Davison AS, Hughes JH, Sutherland H, Wilson PJ, Berry NG, Hughes AT, Milan AM, Jarvis JC, Roberts NB, Ranganath LR, Bou-Gharios G, Gallagher JA. 2020. Studies in alkaptonuria reveal new roles beyond drug clearance for phase I and II biotransformations in tyrosine metabolism Cold Spring Harbor Laboratory DOI Publisher Url
Seaborne RA, Hughes DC, Turner DC, Owens DJ, Baehr LM, Gorski P, Semenova EA, Borisov OV, Larin AK, Popov DV, Generozov EV, Sutherland H, Ahmetov II, Jarvis JC, Bodine SC, Sharples AP. 2019. UBR5 is a Novel E3 Ubiquitin Ligase involved in Skeletal Muscle Hypertrophy and Recovery from Atrophy bioRxiv DOI
Conference publication
Sweeney HL, Masiero S, Carraro U. 2022. The 2022 On-site Padua Days on Muscle and Mobility Medicine hosts the University of Florida Institute of Myology and the Wellstone Center, March 30 - April 3, 2022 at the University of Padua and Thermae of Euganean Hills, Padua, Italy: The collection of abstracts. European journal of translational myology, 32 DOI Author Url Publisher Url
Keenan CM, Sutherland H, Ranganath LR, Jarvis JC, Gallagher JA. 2014. DEVELOPMENT OF OSTEOARTHRITIS IN ALKAPTONURIC MICE RHEUMATOLOGY, Annual Meeting of the British-Society-for-Rheumatology and British-Health-Professionals-in-Rheumatology 53 :131-131 Author Url
Ramnarine I, Ashley Z, Sutherland H, Russold M, Summerfield N, Salmons S, Jarvis J. 2005. Counterpulsation from skeletal muscle ventricles and intra-aortic balloon pumps in the normal and failing circulations CIRCULATION, 78th Annual Scientific Session of the American-Heart-Association 112 :U393-U394 Author Url
Jarvis JC, Sutherland H, Kwende MMN, Mayne CN, Salmons S. 1997. Relationship between working capacity and activation frequency of chronically stimulated skeletal muscle Carpentier AF, Chachques JC, Grandjean PA. CARDIAC BIOASSIST, World Symposium on Cardiomyoplasty and Biomechanical Assist Devices 11 :269-276 Author Url