Pascale Kippelen is a Senior Lecturer in Applied Sport & Exercise Science, with an expertise in Respiratory Physiology. Pascale joined the School of Sport & Exercise Sciences at LJMU in 2024. Prior to LJMU, she worked for 16 years at Brunel University London as: Reader (2020-2024); Senior Lecturer (2008-2020); and Lecturer (2005-2008). During her tenure at Brunel, she served as: Co-Director of the Centre for Physical Activity in Health and Disease (2022-2024); Deputy to the Divisional Lead in Sport, Health and Exercise Sciences (2018-2022); and Co-Director of Undergraduate Studies in Sport, Health and Exercise Sciences (2016-2020).
Pascale’s background is as Exercise and Respiratory Physiologist interested in the health of different human populations, from elite athletes to clinical groups. She attained her undergraduate degree in Sport & Exercise Sciences (Human Performance) at the University of Strasbourg, France, then went on to complete an MSc and a PhD in Exercise and Respiratory Physiology at the University of Montpellier, France. This was followed by 1 ½ years of post-doctoral training at the Department of Respiratory Medicine, Prince Alfred Hospital, Sydney, Australia, under the supervision of Dr Sandra D Anderson. There, Pascale carried out research on the pathophysiology of exercise-induced bronchoconstriction, as well as participated to Phase 3 of the Clinical Trial for Aridole/Osmohale® (an indirect osmotic bronchial challenge test that assists in the diagnosis and management of asthma). On return to Europe, she held an academic position at the University of Aberdeen for 3 yrs. (2005-2008).
Highlighted publications
González-Alonso J, Calbet JAL, Mora-Rodríguez R, Kippelen P. 2023. Pulmonary ventilation and gas exchange during prolonged exercise in humans: Influence of dehydration, hyperthermia and sympathoadrenal activity Experimental Physiology, 108 :188-206 DOI Author Url Publisher Url Public Url
Marshall H, Gibson OR, Romer LM, Illidi C, Hull JH, Kippelen P. 2021. Systemic but not local rehydration restores dehydration-induced changes in pulmonary function in healthy adults Journal of Applied Physiology, 130 :517-527 DOI Author Url Publisher Url Public Url
Simpson AJ, Romer LM, Kippelen P. 2017. Exercise-induced dehydration alters pulmonary function but does not modify airway responsiveness to dry air in athletes with mild asthma Journal of Applied Physiology, 122 :1329-1335 DOI Author Url Publisher Url
Simpson AJ, Bood JR, Anderson SD, Romer LM, Dahlén B, Dahlén SE, Kippelen P. 2016. A standard, single dose of inhaled terbutaline attenuates hyperpnea-induced bronchoconstriction and mast cell activation in athletes Journal of Applied Physiology, 120 :1011-1017 DOI Author Url Publisher Url
Fitch KD, Sue-Chu M, Anderson SD, Boulet LP, Hancox RJ, McKenzie DC, Backer V, Rundell KW, Alonso JM, Kippelen P, Cummiskey JM, Garnier A, Ljungqvist A. 2008. Asthma and the elite athlete: Summary of the International Olympic Committee's Consensus Conference, Lausanne, Switzerland, January 22-24, 2008 Journal of Allergy and Clinical Immunology, 122 DOI Author Url Publisher Url
Journal article
Anderson SD, Kippelen P. 2023. A proposal to account for the stimulus, the mechanism, and the mediators released in exercise-induced bronchoconstriction Frontiers in Allergy, 4 DOI Author Url Publisher Url Public Url
Dickinson J, Gowers W, Sturridge S, Williams N, Kippelen P, Simpson A, Jackson A, Hull JH, Price OJ. 2023. Fractional exhaled nitric oxide in the assessment of exercise-induced bronchoconstriction: A multicenter retrospective analysis of UK-based athletes Scandinavian Journal of Medicine & Science in Sports, 33 :1221-1230 DOI Author Url Publisher Url Public Url
González-Alonso J, Calbet JAL, Mora-Rodríguez R, Kippelen P. 2023. Pulmonary ventilation and gas exchange during prolonged exercise in humans: Influence of dehydration, hyperthermia and sympathoadrenal activity Experimental Physiology, 108 :188-206 DOI Author Url Publisher Url Public Url
Price OJ, Walsted ES, Bonini M, Brannan JD, Bougault V, Carlsen KH, Couto M, Kippelen P, Moreira A, Pite H, Rukhadze M, Hull JH. 2022. Diagnosis and management of allergy and respiratory disorders in sport: An EAACI task force position paper Allergy, 77 :2909-2923 DOI Author Url Publisher Url Public Url
Travers G, Kippelen P, Trangmar SJ, González-Alonso J. 2022. Physiological Function during Exercise and Environmental Stress in Humans—An Integrative View of Body Systems and Homeostasis Cells, 11 DOI Author Url Publisher Url Public Url
Marshall H, Gibson OR, Romer LM, Illidi C, Hull JH, Kippelen P. 2021. Systemic but not local rehydration restores dehydration-induced changes in pulmonary function in healthy adults Journal of Applied Physiology, 130 :517-527 DOI Author Url Publisher Url Public Url
Brannan JD, Kippelen P. 2020. Bronchial Provocation Testing for the Identification of Exercise-Induced Bronchoconstriction Journal of Allergy and Clinical Immunology: In Practice, 8 :2156-2164 DOI Author Url Publisher Url
Simpson AJ, Horne S, Sharp P, Sharps R, Kippelen P. 2019. Effect of Creatine Supplementation on the Airways of Youth Elite Soccer Players Medicine & Science in Sports & Exercise, 51 :1582-1590 DOI Author Url Publisher Url Public Url
Kippelen P, Anderson SD, Hallstrand TS. 2018. Mechanisms and Biomarkers of Exercise-Induced Bronchoconstriction Immunology and Allergy Clinics of North America, 38 :165-182 DOI Author Url Publisher Url
Simpson AJ, Romer LM, Kippelen P. 2017. Exercise-induced dehydration alters pulmonary function but does not modify airway responsiveness to dry air in athletes with mild asthma Journal of Applied Physiology, 122 :1329-1335 DOI Author Url Publisher Url
Kippelen P. 2016. Is there a need to improve asthma diagnosis in young athletes? Expert Review of Respiratory Medicine, 10 :939-941 DOI Author Url Publisher Url
Simpson AJ, Bood JR, Anderson SD, Romer LM, Dahlén B, Dahlén SE, Kippelen P. 2016. A standard, single dose of inhaled terbutaline attenuates hyperpnea-induced bronchoconstriction and mast cell activation in athletes Journal of Applied Physiology, 120 :1011-1017 DOI Author Url Publisher Url
Simpson AJ, Romer LM, Kippelen P. 2015. Self-reported Symptoms after Induced and Inhibited Bronchoconstriction in Athletes Medicine and Science in Sports and Exercise, 47 :2005-2013 DOI Author Url Publisher Url
Kippelen P, Simpson AJ, Romer LM. 2015. Exercise-Induced Dehydration Does Not Affect Airway Responsiveness In Athletes But May Impair Small Airway Function Medicine & Science in Sports & Exercise, 47 :722-722 DOI Publisher Url
Kippelen P, Tufvesson E, Ali L, Bjermer L, Anderson SD. 2013. Urinary CC16 after challenge with dry air hyperpnoea and mannitol in recreational summer athletes Respiratory Medicine, 107 :1837-1844 DOI Author Url Publisher Url
Simpson AJ, Tufvesson E, Anderson SD, Romer LM, Bjermer L, Kippelen P. 2013. Effect of terbutaline on hyperpnoea-induced bronchoconstriction and urinary club cell protein 16 in athletes Journal of Applied Physiology, 115 :1450-1456 DOI Author Url Publisher Url
Kippelen P, Anderson SD. 2013. Pathogenesis of Exercise-Induced Bronchoconstriction Immunology and Allergy Clinics of North America, 33 :299-312 DOI Author Url Publisher Url
Anderson SD, Kippelen P. 2013. Assessment of EIB. What You Need to Know to Optimize Test Results. Immunology and Allergy Clinics of North America, 33 :363-380 DOI Author Url Publisher Url
Hallstrand TS, Kippelen P, Larsson J, Bougault V, van Leeuwen JC, Driessen JMM, Brannan JD. 2013. Where to from Here for Exercise-Induced Bronchoconstriction. The Unanswered Questions Immunology and Allergy Clinics of North America, 33 :423-442 DOI Author Url Publisher Url
Kippelen P, Fitch KD, Anderson SD, Bougault V, Boulet LP, Rundell KW, Sue-Chu M, McKenzie DC. 2012. Respiratory health of elite athletes - Preventing airway injury: A critical review British Journal of Sports Medicine, 46 :471-476 DOI Author Url Publisher Url
Anderson SD, Kippelen P. 2012. Assessment and prevention of exercise-induced bronchoconstriction British Journal of Sports Medicine, 46 :391-396 DOI Author Url Publisher Url
Kippelen P, Anderson SD. 2012. Airway injury during high-level exercise British Journal of Sports Medicine, 46 :385-390 DOI Author Url Publisher Url
Ansley L, Kippelen P, Dickinson J, Hull JHK. 2012. Misdiagnosis of exercise-induced bronchoconstriction in professional soccer players Allergy: European Journal of Allergy and Clinical Immunology, 67 :390-395 DOI
Ansley L, Kippelen P, Dickinson JW, Hull J. 2011. Misdiagnosis of exercise induced bronchoconstriction in professional soccer players Allergy, DOI Author Url Publisher Url
Bolger C, Tufvesson E, Anderson SD, Devereux G, Ayres JG, Bjermer L, Sue-Chu M, Kippelen P. 2011. Effect of inspired air conditions on exercise-induced bronchoconstriction and urinary CC16 levels in athletes Journal of Applied Physiology, 111 :1059-1065 DOI Author Url Publisher Url
Bolger C, Tufvesson E, Sue-Chu M, Devereux G, Ayres JG, Bjermer L, Kippelen P. 2011. Hyperpnea-induced bronchoconstriction and urinary CC16 levels in athletes Medicine and Science in Sports and Exercise, 43 :1207-1213 DOI Author Url Publisher Url
Anderson SD, Kippelen P. 2010. Stimulus and mechanisms of exercise-induced bronchoconstriction Breathe, 7 :25-33 DOI Publisher Url
Kippelen P, Larsson J, Anderson SD, Brannan JD, Dahlén B, Dahlén SE. 2010. Effect of sodium cromoglycate on mast cell mediators during hyperpnea in athletes Medicine and Science in Sports and Exercise, 42 :1853-1860 DOI Author Url Publisher Url
Kippelen P, Larsson J, Anderson SD, Brannan JD, Delin I, Dahlen B, Dahlen SE. 2010. Acute effects of beclomethasone on hyperpnea-induced bronchoconstriction Medicine and Science in Sports and Exercise, 42 :273-280 DOI Author Url Publisher Url
Bougault V, Kippelen P. 2009. Respiratory health of athletes Revue des Maladies Respiratoires Actualites, 1 DOI Publisher Url
Anderson SD, Kippelen P. 2008. Airway injury as a mechanism for exercise-induced bronchoconstriction in elite athletes Journal of Allergy and Clinical Immunology, 122 :225-235 DOI Author Url Publisher Url
Fitch KD, Sue-Chu M, Anderson SD, Boulet LP, Hancox RJ, McKenzie DC, Backer V, Rundell KW, Alonso JM, Kippelen P, Cummiskey JM, Garnier A, Ljungqvist A. 2008. Asthma and the elite athlete: Summary of the International Olympic Committee's Consensus Conference, Lausanne, Switzerland, January 22-24, 2008 Journal of Allergy and Clinical Immunology, 122 DOI Author Url Publisher Url
Kippelen P, Delin I, Brannan JD, Larsson J, Dahlén B, Kumlin M, Anderson SD, Dahlén S-E. 2007. Rapid Effects Of Inhaled Beclomethasone On Hyperpnea-Induced Bronchoconstriction And Mast Cell Mediator Release In Athletes Medicine & Science in Sports & Exercise, 39 :S341-S341 DOI Publisher Url
Anderson SD, Sue-Chu M, Perry CP, Gratziou C, Kippelen P, McKenzie DC, Beck KC, Fitch KD. 2006. Bronchial challenges in athletes applying to inhale a β
Kippelen P, Housset B, Rochcongar P, Friemel F, Godard P. 2006. Methacholine challenge testing in olympic athletes Revue des maladies respiratoires, 23 :27-28 DOI Author Url Publisher Url
Brannan JD, Anderson SD, Perry CP, Freed-Martens R, Lassig AR, Charlton B, Hurwitz M, Furler J, Sunderland J, Tourniea W, Nogrady S, Young I, Briffa P, Kippelen P, Turton J, McNamara S, Peters M, Rogers P, Plowman L, Seccombe L, Cossa G, Veitch E, Berend N, Schoeffel R, Simmul R, Keatley L, Henry R, Dixon S, O'Donovan B, Martin B, Numa A, Boynton A, Morton J, Belessis Y, Wheatley JR, West S, Bovington K, Serwach N, Lee S, Middleton P, Mayrhofer P, Van Asperen P, Nassar S, McArthur M, De Torres C, McKay K, Fitzgerald D, Kennedy B, Gibson P, Borgas T, Smart J, Bell N, Sarunac J, Robertson C, Smith J, Sheridan S, Roberts M, Stirling R, Thompson B, Ellis M, Borg B, Jack S, Hartley F, Khov S, Hukins C, Eckert B, Ruedinger L, McLennan S, Zimmerman P, McElrea M, Dent A, Rodwell L. 2005. The safety and efficacy of inhaled dry powder mannitol as a bronchial provocation test for airway hyperresponsiveness: A phase 3 comparison study with hypertonic (4.5%) saline Respiratory Research, 6 DOI Author Url Publisher Url
Kippelen P, Caillaud C, Robert E, Connes P, Godard P, Prefaut C. 2005. Effect of endurance training on lung function: A one year study British Journal of Sports Medicine, 39 :617-621 DOI Author Url Publisher Url
Durand F, Kippelen P, Ceugniet F, Gomez VR, Desnot P, Poulain M, Préfaut C. 2005. Undiagnosed exercise-induced bronchoconstriction in ski-mountaineers International Journal of Sports Medicine, 26 :233-237 DOI Author Url Publisher Url
Anderson SD, Kippelen P. 2005. Exercise-induced bronchoconstriction: Pathogenesis Current Allergy and Asthma Reports, 5 :116-122 DOI Author Url Publisher Url
Connes P, Bouix D, Durand F, Kippelen P, Mercier J, Prefaut C, Brun JF, Caillaud C. 2004. Is hemoglobin desaturation related to blood viscosity in athletes during exercise? International Journal of Sports Medicine, 25 :569-574 DOI Author Url Publisher Url
Connes P, Bouix D, Py G, Caillaud C, Kippelen P, Brun JF, Varray A, Prefaut C, Mercier J. 2004. Does exercise-induced hypoxemia modify lactate influx into erythrocytes and hemorheological parameters in athletes? Journal of Applied Physiology, 97 :1053-1058 DOI Author Url Publisher Url
Kippelen P, Caillaud C, Coste O, Godard P, Préfaut C. 2004. Asthma and Exercise-Induced Bronchoconstriction in Amateur Endurance-Trained Athletes International Journal of Sports Medicine, 25 :130-132 DOI Author Url Publisher Url
Kippelen P, Friemel F, Godard P. 2003. Asthma in athletes Revue des Maladies Respiratoires, 20 :385-397 Author Url
Kippelen P, Friemel F, Godard P. 2003. Asthma in athletes REVUE DES MALADIES RESPIRATOIRES, 20 :385-397
Kippelen P, Caillaud C, Robert E, Masmoudi K, Préfaut C. 2002. Exhaled nitric oxide level during and after heavy exercise in athletes with exercise-induced hypoxaemia Pflugers Archiv European Journal of Physiology, 444 :397-404 DOI Author Url Publisher Url
Conference publication
Dickinson J, Gowers W, Sturridge S, Williams N, Kippelen P, Simpson A, Jackson A, Hull J, Price O. 2022. Fractional exhaled nitric oxide in the assessment of exercise-induced bronchoconstriction: a multicentre retrospective analysis of UK-based athletes 01.05 - Clinical respiratory physiology, exercise and functional imaging, ERS International Congress 2022 abstracts :1017-1017 DOI Publisher Url
Marshall H, Romer LM, Hull JH, Gibson OR, Kippelen P. 2018. P225 Effects of systemic dehydration and subsequent systemic or local rehydration on lung function in healthy individuals An update in lung physiology, British Thoracic Society Winter Meeting 2018, QEII Centre, Broad Sanctuary, Westminster, London SW1P 3EE, 5 to 7 December 2018, Programme and Abstracts :A223-A224 DOI Publisher Url
Chapters
Kippelen P, Simpson A. 2020. Epidemiology and pathophysiology of exercise-induced bronchoconstriction in athletes Complete Guide to Respiratory Care in Athletes :41-54 Routledge DOI Publisher Url
Sue‐Chu M, Kippelen P. 2020. Effects of Cold and Heat on the Lung :653-659 Wiley 9781118597354 DOI Publisher Url
Conference presentation:
Cold, heat and the lungs, European College of Sport Science annual congress, Oral presentation. 2022
Effects of systemic and local (airway) dehydration on pulmonary function and ventilatory responses to exercise, European College of Sport Science annual congress, Oral presentation. 2021
Asthma in athletes: what can we do?, European Athletics High Performance Webinar Series, Oral presentation. 2020
External committees:
Reviewing Panel, European College of Sport Science (ECSS), Invited member. 2021
Committee in Sports & Allergy, World Allergy Organization, Invited member. 2018
Respiratory Steering Panel, UK Anti-Doping, Invited member. 2018
Asthma Advisory Panel, Amateur Swimming Association, Invited member. 2009
Independent Asthma Panel, International Olympic Committee – Medical Commission, Invited member. 2004
Teaching qualification:
Fellow of the Higher Education Academy. 2017
Public engagement:
Performance art: music, dance, drama, etc., City dwellers and athletes, Associate Scientist, Invisible Dust, Pascale was an Associate Scientist to ‘Invisible Dust’ – a high-profile project run ahead of the 2012 London Olympics by curator Alice Sharp and jointly funded by The Wellcome Trust and the Arts Council England (Faisal Abdu'Allah - Double Pendulum - Invisible Dust). The project involved outreach activities with young people from East London, as well as a collaboration with the prominent British artist, Faisal Abdu’Allah; this led to the creation of ‘Double Pendulum’, a film that explored the effects of pollution on the respiratory health of athletes. The film was screened as part of the CREATE11 festival at the ViewTube, in June 2012. It subsequently won the prestigious Lord Mayor of London ‘Sustainability City’ award for ‘Air Quality’, https://invisibledust.com/projects/faisal-abduallah-double-pendulum/. 2012
Other Professional Activity:
Co-author of the Physical Activity and Respiratory Disease Factsheet, Motivate-2-Move, Health Education and Improvement Wales, https://gpcpd.heiw.wales/clinical/motivate-2-move/chapter-12-respiratory-disease/.
Fellowships:
Fellow, European College of Sport Science.
Membership of professional bodies:
Member, British Thoracic Society.
Member, European College of Sport Science.
Member, European Respiratory Society.
Member, The Physiological Society.