Prof Gillian Hutcheon
Pharmacy and Biomolecular Sciences
Faculty of Science
Email: G.A.Hutcheon@ljmu.ac.uk
Telephone: 0151 231 2130
staff page
ORCID
I joined LJMU in 1999 as a Lecturer in Bioorganic Chemistry and am now a Professor in Pharmaceutical Biomaterials My research interests include the use of biodegradable polymers for the micro and nanoparticle delivery of drugs and biological molecules. Specific examples of ongoing projects include the nasal delivery of novel CGRP-targeted peptide antagonists to treat migraine.
Between 2016 and 2021 I was seconded as Head of the LJMU Institute for Health Research which involved the strategic facilitation of healthcare research across all 5 Faculties and provided me with an appreciation of research across different health professions and sectors.
During 2022 I undertook a secondment with Liverpool Health Partners as Head of Education and Research Capacity Building. This involved working with local NHS trusts, HEIS and other health and social care providers around improving system-wide capacity for health and care research. This has led onto new research projects around the development of the Health and Care Research Workforce and the growth of an IHR Interest group in Workforce Development.
Degrees
1996, University of Strathclyde, United Kingdom, PhD: Fundamental studies of protein hydration and solvation in organic media
1993, University of Strathclyde, United Kingdom, B.Sc. (Hons) Forensic and Analytical Chemistry
Certifications
2018, Institute of Learning and Management, United Kingdom, ILM Level 5
2012, The Higher Education Academy, Uk, Fellow of the Higher Education Academy
2009, Royal Society of Chemistry, Fellow of the Royal Society of Chemistry
2002, The Higher Education Academy, UK, Associate Teacher in Higher Education
1997, Royal Society of Chemistry, Chartered Chemist
Academic appointments
Professor of Pharmaceutical Biomaterials, School of Pharmacy and Biomedical Sciences, Liverpool John Moores University, 2018 - present
Head of Institute for Health Research, Liverpool John Moores University, Liverpool, 2016 - 2021
Reader, School of Pharmacy and biomolecular Sciences, Liverpool John Moores University, 2009 - 2018
lecturar/senior lecturar, School of Pharmacy and Chemistry, Liverpool John Moores University, 1999 - 2008
Postdoctoral Research Fellow, School of Biomedical Sciences and School of Pharmacy, University of Nottingham, 1997 - 1999
Postdoctoral Research Assistant, Department of Pure and Applied Chemistry, University of Strathclyde, 1996 - 1997
Highlighted publications
Almurshedi AS, Radwan M, Omar S, Alaiya AA, Badran MM, Elsaghire H, Saleem IY, Hutcheon GA. 2018. A novel Ph-sensitive liposome to trigger delivery of afatinib to cancer cells: Impact on lung cancer therapy Journal of Molecular Liquids, 259 :154-166 DOI Author Url Publisher Url Public Url
Journal article
Killoran PM, Capel V, D'Aloisio V, Schofield A, Aczél T, Bölcskei K, Helyes Z, von Mentzer B, Kendall DA, Coxon CR, Hutcheon GA. 2023. Novel peptide calcitonin gene-related peptide antagonists for migraine therapy. The Journal of pharmacy and pharmacology, :1-9 DOI Author Url Publisher Url Public Url
D'Aloisio V, Schofield A, Kendall DA, Hutcheon GA, Coxon CR. 2023. The development and optimisation of an HPLC-based in vitro serum stability assay for a calcitonin gene-related peptide receptor antagonist peptide Journal of Peptide Science, :e3539 DOI Author Url Publisher Url Public Url
Muller AG, Sarker SD, Fatokun AA, Hutcheon GA. 2022. Formulation of resveratrol into PGA-co-PDL nanoparticles increases its cytotoxic potency against lung cancer cells RPS Pharmacy and Pharmacology Reports, 2 DOI Publisher Url Public Url
D'Aloisio V, Dognini P, Hutcheon GA, Coxon CR. 2021. PepTherDia: database and structural composition analysis of approved peptide therapeutics and diagnostics. Drug Discovery Today, DOI Author Url Publisher Url Public Url
von Mentzer B, Russo AF, Zhang Z, Kuburas A, Killoran PM, D'Aloisio V, Nizic L, Capel V, Kendall DA, Coxon CR, Hutcheon GA. 2020. A CGRP receptor antagonist peptide formulated for nasal administration to treat migraine Journal of Pharmacy and Pharmacology, DOI Author Url Publisher Url Public Url
Mohamed A, Pekoz AY, Ross K, Hutcheon GA, Saleem IY. 2019. Pulmonary delivery of Nanocomposite Microparticles (NCMPs) incorporating miR-146a for treatment of COPD. International Journal of Pharmaceutics, 569 DOI Author Url Publisher Url Public Url
Hamilton AR, Roberts M, Hutcheon GA, Gaskell EE. 2019. Formulation and antibacterial properties of clay mineral-tetracycline and -doxycycline composites Applied Clay Science, 179 DOI Author Url Publisher Url Public Url
Muller AG, Sarker SD, Saleem IY, Hutcheon GA. 2019. Delivery of natural phenolic compounds for the potential treatment of lung cancer. DARU Journal of Faculty of Pharmacy, DOI Author Url Publisher Url Public Url
Mohamed A, Kunda NK, Ross K, Hutcheon GA, Saleem IY. 2019. Polymeric Nanoparticles for the Delivery of miRNA to Treat Chronic Obstructive Pulmonary Disease (COPD). European Journal of Pharmaceutics and Biopharmaceutics, 136 :1-8 DOI Author Url Publisher Url Public Url
Almurshedi AS, Radwan M, Omar S, Alaiya AA, Badran MM, Elsaghire H, Saleem IY, Hutcheon GA. 2018. A novel Ph-sensitive liposome to trigger delivery of afatinib to cancer cells: Impact on lung cancer therapy Journal of Molecular Liquids, 259 :154-166 DOI Author Url Publisher Url Public Url
Hutcheon GA, Dempster NM, Roberts M, Gaskell EE, Kianfar F. 2017. Lyophilised Biopolymer-Clay Hydrogels for Drug Delivery Journal of Novel Drug Research, 1 DOI Public Url
Alfagih IM, Kunda NK, Alanazi F, Dennison SR, Somavarapu S, Hutcheon GA, Saleem IY. 2015. Pulmonary Delivery of Proteins Using Nanocomposite Microcarriers. Journal of Pharmaceutical Sciences, :1-13 DOI Author Url Publisher Url Public Url
Kunda NK, Alfagih IM, Hutcheon GA, Saleem IY, Miyaji EN, Figueiredo DB, Gonçalves VM, Ferreira DM, Dennison SR, Somavarapu S. 2015. Pulmonary dry powder vaccine of pneumococcal antigen loaded nanoparticles International Journal of Pharmaceutics, 495 :903-912 DOI Author Url Publisher Url Public Url
Kunda NK, Alfagih IM, Dennison SR, Somavarapu S, Merchant Z, Hutcheon GA, Saleem IY. 2015. Dry powder pulmonary delivery of cationic PGA-co-PDL nanoparticles with surface adsorbed model protein International Journal of Pharmaceutics, 492 :213-222 DOI Author Url Publisher Url Public Url
Ghazal HS, Dyas AM, Ford JL, Hutcheon GA. 2015. The impact of food components on the intrinsic dissolution rate of ketoconazole DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 41 :1647-1654 DOI Author Url Publisher Url Public Url
Kunda NK, Alfagih IM, Dennison SR, Tawfeek HM, Somavarapu S, Hutcheon GA, Saleem IY. 2014. Bovine Serum Albumin Adsorbed PGA-co-PDL Nanocarriers for Vaccine Delivery via Dry Powder Inhalation Pharmaceutical Research, 32 :1341-1353 DOI Author Url Publisher Url Public Url
Tawfeek HM, Khidr SH, Samy EM, Ahmed SM, Gaskell EE, Hutcheon GA. 2014. Evaluation of biodegradable polyester-co-lactone microparticles for protein delivery. Drug Dev Ind Pharm, 40 :1213-1222 DOI Author Url Publisher Url Public Url
Hamilton AR, Hutcheon GA, Roberts M, Gaskell EE. 2014. Formulation and antibacterial profiles of clay-ciprofloxacin composites APPLIED CLAY SCIENCE, 87 :129-135 DOI Author Url Publisher Url
Jan SU, Khan GM, Hussain I, Gaskell EE, Hutcheon GH. 2013. Synthesis, conjugation and evaluation of some novel polymers and their micro particles for sustained release drug formulations Pakistan Journal of Pharmaceutical Sciences, 26 :741-746 Author Url
Kunda NK, Somavarapu S, Gordon SB, Hutcheon GA, Saleem IY. 2013. Nanocarriers targeting dendritic cells for pulmonary vaccine delivery. Pharm Res, 30 :325-341 DOI Author Url Publisher Url Public Url
Kunda NK, Somavarapu S, Gordon SB, Hutcheon GA, Saleem IY. 2013. Nanocarriers Targeting Dendritic Cells for Pulmonary Vaccine Delivery PHARMACEUTICAL RESEARCH, 30 :1-17 Publisher Url Public Url
Tawfeek HM, Evans AR, Iftikhar A, Mohammed AR, Shabir A, Somavarapu S, Hutcheon GA, Saleem IY. 2013. Dry powder inhalation of macromolecules using novel PEG-co-polyester microparticle carriers. Int J Pharm, 441 :611-619 DOI Author Url Publisher Url Public Url
Khamar D, Bradshaw IJ, Hutcheon GA, Seton L. 2012. Solid State Transformations Mediated by a Kinetically Stable Form CRYSTAL GROWTH & DESIGN, 12 :109-118 DOI Author Url Publisher Url
Seton L, Khamar D, Bradshaw I, Hutcheon G. 2012. Processing induced transformations: Phase impurities introduced during hydration/dehydration CHEMICAL ENGINEERING SCIENCE, 77 :57-64 DOI Author Url Publisher Url
Khamar D, Pritchard RG, Bradshaw IJ, Hutcheon GA, Seton L. 2011. Polymorphs of anhydrous theophylline: stable form IV consists of dimer pairs and metastable form I consists of hydrogen-bonded chains. Acta Crystallogr C, 67 :o496-o499 DOI Author Url Publisher Url Public Url
Al-Fagih IM, Alanazi FK, Hutcheon GA, Saleem IY. 2011. Recent Advances Using Supercritical Fluid Techniques for Pulmonary Administration of Macromolecules via Dry Powder Formulations Drug Delivery Letters, 1 :128-134 Publisher Url Public Url
Tawfeek HM, Khidr SH, Samy EM, Ahmed SM, Murphy MF, Mohammad A, Shabir A, Hutcheon GA, Saleem IY. 2011. Poly(glycerol adipate-co-ω-pentadecalactone) spray dried microparticles as carriers for pulmonary delivery Pharmacological Research, :1-12 DOI
Seton L, Khamar D, Bradshaw IJ, Hutcheon GA. 2010. Solid State Forms of Theophylline: Presenting a New Anhydrous Polymorph CRYSTAL GROWTH & DESIGN, 10 :3879-3886 DOI Author Url Publisher Url
Gaskell EE, Sihanonth P, Rostron C, Hutcheon GA, Hobbs G. 2010. Isolation and identification of mucinolytic actinomycetes. Antonie Van Leeuwenhoek, 97 :211-220 DOI Author Url Publisher Url
Thompson CJ, Hansford D, Higgins S, Rostron C, Hutcheon GA, Munday DL. 2009. Preparation and evaluation of microspheres prepared from novel polyester-ibuprofen conjugates blended with non-conjugated ibuprofen. J Microencapsul, 26 :676-683 DOI Author Url Publisher Url
Ghazal HS, Dyas AM, Ford JL, Hutcheon GA. 2009. In vitro evaluation of the dissolution behaviour of itraconazole in bio-relevant media. Int J Pharm, 366 :117-123 DOI Author Url Publisher Url
Thompson CJ, Hansford D, Higgins S, Rostron C, Hutcheon GA, Munday DL. 2009. Preparation and evaluation of microspheres prepared from novel polyester-ibuprofen conjugates blended with non-conjugated ibuprofen. J Microencapsul, :1-8 DOI Publisher Url
Orafai H, Kallinteri P, Garnett M, Huggins S, Hutcheon G, Pourcain C. 2008. Novel poly (glycerol-adipate) polymers used for nanoparticle making: A study of surface free energy IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 7 :11-19 Author Url
Thompson CJ, Hansford D, Munday DL, Higgins S, Rostron C, Hutcheon GA. 2008. Synthesis and evaluation of novel polyester-ibuprofen conjugates for modified drug release. Drug Dev Ind Pharm, 34 :877-884 DOI Author Url Publisher Url
Gaskell EE, Hobbs G, Rostron C, Hutcheon GA. 2008. Encapsulation and release of alpha-chymotrypsin from poly(glycerol adipate-co-omega-pentadecalactone) microparticles. J Microencapsul, 25 :187-195 DOI Author Url Publisher Url Public Url
Puri S, Kallinteri P, Higgins S, Hutcheon GA, Garnett MC. 2008. Drug incorporation and release of water soluble drugs from novel functionalized poly(glycerol adipate) nanoparticles. J Control Release, 125 :59-67 DOI Author Url Publisher Url
Thompson CJ, Hansford D, Higgins S, Rostron C, Hutcheon GA, Munday DL. 2007. Evaluation of ibuprofen-loaded microspheres prepared from novel copolyesters. Int J Pharm, 329 :53-61 DOI Author Url Publisher Url
Long J, Hutcheon GA, Cooper AI. 2007. Combinatorial discovery of reusable noncovalent supports for enzyme immobilization and nonaqueous catalysis. J Comb Chem, 9 :399-406 DOI Author Url Publisher Url
Meng W, Parker TL, Kallinteri P, Walker DA, Higgins S, Hutcheon GA, Garnett MC. 2006. Uptake and metabolism of novel biodegradable poly (glycerol-adipate) nanoparticles in DAOY monolayer. J Control Release, 116 :314-321 DOI Author Url Publisher Url
Thompson CJ, Hansford D, Higgins S, Hutcheon GA, Rostron C, Munday DL. 2006. Enzymatic synthesis and evaluation of new novel omega-pentadecalactone polymers for the production of biodegradable microspheres. J Microencapsul, 23 :213-226 DOI Author Url Publisher Url
Kallinteri P, Higgins S, Hutcheon GA, St Pourçain CB, Garnett MC. 2005. Novel functionalized biodegradable polymers for nanoparticle drug delivery systems. Biomacromolecules, 6 :1885-1894 DOI Author Url Publisher Url
Hutcheon GA, Messiou C, Wyre RM, Davies MC, Downes S. 2001. Water absorption and surface properties of novel poly(ethylmethacrylate) polymer systems for use in bone and cartilage repair. Biomaterials, 22 :667-676 DOI Author Url Publisher Url
Hutcheon GA, Parker MC, Moore BD. 2000. Measuring enzyme motility in organic media using novel H-D exchange methodology. Biotechnol Bioeng, 70 :262-269 DOI Author Url Publisher Url
Hutcheon GA, Downes S, Davies MC. 1998. Interactions of chondrocytes with methacrylate copolymers. J Mater Sci Mater Med, 9 :815-818 DOI Author Url Publisher Url
Hutcheon GA, Parker MC, James A, Moore BD. 1997. Methanol dramatically enhances serine protease activity under anhydrous conditions CHEMICAL COMMUNICATIONS, :931-932 DOI Author Url Publisher Url
Hutcheon GA, Halling PJ, Moore BD. 1997. Measurement and control of hydration in nonaqueous biocatalysis Rubin B, Dennis EA. LIPASES, PT B, 286 :465-472 DOI Author Url Publisher Url
Partridge J, Hutcheon GA, Moore BD, Halling PJ. 1996. Exploiting hydration hysteresis for high activity of cross-linked subtilisin crystals in acetonitrile JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 118 :12873-12877 DOI Author Url Publisher Url
Tawfeek H, Khidr S, Samy E, Ahmed S, Murphy M, Mohammed A, Shabir A, Hutcheon G, Saleem I. Poly(Glycerol Adipate-co-ω-Pentadecalactone) Spray-Dried Microparticles as Sustained Release Carriers for Pulmonary Delivery Pharmaceutical Research, 28 :2086-2097 DOI Author Url Publisher Url Public Url
Kianfar F, Dempster N, Gaskell E, Roberts M, Hutcheon GA. Lyophilised biopolymer-clay hydrogels for drug delivery Madridge Journal of Novel Drug Research, 1 :1-9 DOI Publisher Url
Chapters
Gupta A, Maheshwari R, Kuche K, Hutcheon GA, Tekade RK. 2019. Regulatory assessment for controlled drug delivery products Drug Delivery Systems :721-741 DOI Publisher Url
Chawla S, Tekade M, Maheshwari R, Chourasiya Y, Hutcheon GA, Tekade RK. 2019. Engineered Mesenchymal Stem Cells as Nanocarriers for Cancer Therapy and Diagnosis Biomaterials and Bionanotechnology :19-56 DOI Publisher Url
Gupta A, Maheshwari R, Kuche K, Hutcheon GA, Tekade RK. 2019. Chapter 15 Regulatory assessment for controlled drug delivery products Drug Delivery Systems :721-741 Elsevier DOI
Chawla S, Tekade M, Maheshwari R, Chourasiya Y, Hutcheon GA, Tekade RK. 2019. Chapter 2 Engineered Mesenchymal Stem Cells as Nanocarriers for Cancer Therapy and Diagnosis Biomaterials and Bionanotechnology :19-56 Elsevier DOI
Kunda N, Alfagih I, Saleem I, Hutcheon G. 2015. Polymer-based Delivery Systems for the Pulmonary Delivery of Biopharmaceuticals Nokhodchi A, Martin G. Pulmonary Drug Delivery: Advances and Challenges John Wiley & Sons, Ltd DOI Publisher Url
Conference publication
Osman N, Sexton D, Hutcheon G, Saleem I. 2017. COMPARATIVE NANOTOXICOLOGY OF POLYMERIC NANOCARRIERS WITH DIFFERENT SURFACE CHARGE AGAINST HUMAN LUNG EPITHELIAL CELLS JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 30 :A17-A18 Author Url
Osman N, Hilal M, Mohamed S, Dawood A, ritchie K, Saleem I, hutcheon G. 2015. In-vitro Stability and Degradation of PLGA and PGA-co-PDL Microparticles for Pulmonary Drug Delivery Drug Delivery to the Lungs
Osman N, Hilal M, Mohamed S, Dawood A, Ritchie K, Saleem I, hutcheon G. 2015. In vitro Stability and Degradation of PLGA and PGA-co-PDL Microparticles for Drug Delivery Controlled Release Annual Meeting Author Url
kunda N, alfagih I, Alanazi F, hutcheon G, saleem I. 2015. Comparison of Protein Delivery via Nanocomposite Microcarriers for Pulmonary Vaccine Delivery
Alfagih IM. 2014. Cationic PGA-co-PDL nanocomposite microparticles for antigen delivery via inhalation Drug Delivery to the Lungs DDL25 Author Url
Alfagih I, Kunda N, Alanazi F, Hutcheon G, saleem I. 2014. Cationic PGA-co-PDL nanocomposite microparticles for antigen delivery via inhalation
kunda N, Somavarapu S, Gordon SB, Hutcheon G, Saleem I. 2013. Protein Adsorbed PGA-co-PDL Nanocarriers for Vaccine Delivery AAPS Annual Meeting and Exposition
Kunda NK, Alfagih I, Somavarapu S, Hutcheon G, Saleem I. 2013. Pulmonary vaccine delivery of protein adsorbed PGA-co-PDL nanocomposite microparticles Journal of Aerosol Medicine and Pulmonary Drug Delivery, 26 :A-1-A-29 DOI Publisher Url
saleem I, hutcheon G, Satyanarayana S. 2013. Pulmonary delivery of beclometasone loaded PGA-co-PDL nanocomposite microparticles Journal of Aerosol Medicine and Pulmonary Drug Delivery, 26 :A-1-A-27 DOI Publisher Url
Alfagih IM, Alanazi FK, Kunda NK, Hutcheon GA, Saleem IY. 2012. Protein Loaded PGA-co-PDL Nanocomposite Microparticles for Inhalation Drug Delivery to the Lungs DDL23 Author Url
kunda NK, Alfagih IM, Somavarapu S, Hutcheon GA, Saleem I. 2012. Pulmonary Vaccine Delivery of Protein Adsorbed PGA-co-PDL Nanocomposite Microparticles Drug Delivery to the Lungs - DDL23 Author Url
Ismail FMD, Tawfeek HM, Hutcheon GA, Saleem IY . 2011. Pulmonary delivery of encapsulated chloroquine phosphate using polyester polymer-based microparticles for potential treatment of lung cancers Journal of Aerosol Medicine and Pulmonary Drug Delivery, 24 :303-334
Tawfeek H, Khidr SH, Samy EM, Ahmed SM, Hutcheon G, Saleem I. 2011. Effect of PEGylation on spray dried PGA-co-PDL pulmonary carrier microparticles Journal of Aerosol Medicine and Pulmonary Drug Delivery, 24 :303-334
Tawfeek HM, Khidr SH, Samy EM, Ahmed SM, Akram K, Mohammed AR, Gaskell EE, Hutcheon G, Saleem I. 2010. Optimisation of polyester based microparticles as carriers for pulmonary drug delivery Drug Delivery to the Lungs
Tawfeek HM, Khidr SH, Samy EM, Ahmed SM, Akram K, Mohammed AR, Gaskel EE, Hutcheon GA, Saleem IY. 2010. Optimisation of Polyester Based Microparticles as Carriers for Pulmonary Drug Delivery JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 23 :430-430
Tawfeek HM, Khidr SH, Samy EM, Ahmed SM, Shabir A, Mohammed AR, Hutcheon GA, Saleem I. 2010. Pulmonary delivery of alpha-chymotrypsin via novel polyester microparticles JOURNAL OF PHARMACY AND PHARMACOLOGY, 62 :1294-1295 Author Url
Khamar D, Seton L, Bradshaw I, Hutcheon G. 2010. Generation and characterisation of new anhydrous polymorph of theophylline JOURNAL OF PHARMACY AND PHARMACOLOGY, 62 :1333-1334 Author Url
Tawfeek HM, Khidr SH, Samy EM, Ahmed SM, Evans A, Gaskell EE, Hutcheon GA. 2010. Encapsulation, release, bioactivity and cytotoxicity of lysozyme loaded poly(glycerol adipte-co-omega-pentadecalactone) microparticles JOURNAL OF PHARMACY AND PHARMACOLOGY, 62 :1431-1432 Author Url
Tawfeek H, Khidr S, Samy E, Ahmed S, Hutcheon G, Saleem I. 2010. Enhancing the Aerosolisation Proprieties of Polyester based Microparticles as Novel Carriers for Dry Powder Inhalation 37th Annual Meeting & Exposition of the Controlled Release Society
Tawfeek H, Khidr S, Samy EM, Ahmed SM, Gaskell EE, Hutcheon G, Saleem I. 2010. PGA-co-PDL as a Novel Carrier for Pulmonary Drug Delivery 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology
McAllister L, Evans A, Hutcheon G, Gaskell E. 2009. Encapsulation of epirubicin for the treatment of cancer JOURNAL OF PHARMACY AND PHARMACOLOGY, 61 :A82-A82 Author Url
Hutcheon GA, Gaskell E, Iftikhar A, Rostron C. 2008. Overcoming the mucin barrier in the treatment of pulmonary cystic fibrosis JOURNAL OF PHARMACY AND PHARMACOLOGY, 60 :A11-A11 Author Url
Iftikhar A, Gaskell E, Hutcheon GA, Rostron C. 2008. The stability of biodegradable polyesters and polyester-co-lactones utilized for drug delivery JOURNAL OF PHARMACY AND PHARMACOLOGY, 60 :A58-A58 Author Url
Ghazal H, Dyas AM, Ford JL, Hutcheon GA. 2007. The intrinsic dissolution rate of ketoconazole in proteinaceous biorelevant media JOURNAL OF PHARMACY AND PHARMACOLOGY, 59 :A46-A46 Author Url
Thompson CJ, Hansford D, Munday DL, Higgins S, Hutcheon GA, Rostron C. 2006. Preparation and characterisation of microspheres of a novel polyester polymer conjugated to ibuprofen JOURNAL OF PHARMACY AND PHARMACOLOGY, 58 :A15-A15 Author Url
Gaskell E, Hobbs G, Rostron C, Hutcheon GA. 2006. Encapsulation of mucinolytic enzymes for treatment of cystic fibrosis JOURNAL OF PHARMACY AND PHARMACOLOGY, 58 :A67-A67 Author Url
Gaskell E, Hobbs G, Rostron C, Hutcheon G. 2005. Use of functional polymers for treatment of pulmonary cystic fibrosis JOURNAL OF PHARMACY AND PHARMACOLOGY, 57 :S5-S5 Author Url
Gaskell E, Hobbs G, Rostron C, Hutcheon G. 2005. Use of functional polymers for treatment of pulmonary cystic fibrosis JOURNAL OF PHARMACY AND PHARMACOLOGY, 57 :S60-S60 Author Url
Hansford D, Higgins S, Hutcheon GA, Munday DL, Rostron C, Thompson CJ. 2005. Synthesis and characterisation of novel polyesters for the production of biodegradable microspheres JOURNAL OF PHARMACY AND PHARMACOLOGY, 57 :S63-S63 Author Url
Puri S, Kallinteri P, Higgins SH, Hutcheon GA, Garnett MC. 2005. Drug incorporation and release from functionalized poly glycerol adipate nanoparticles JOURNAL OF PHARMACY AND PHARMACOLOGY, 57 :S21-S22 Author Url
Meng W, Parker TL, Kallinteri P, Hutcheon GA, Higgins S, Walker DA, Walker DA, Garnett MC. 2005. Uptake and drug delivery using biodegradable nanoparticles in monolayers and organotypic brain slices NEURO-ONCOLOGY, 2nd Quadrennial Meeting of the World-Federation-of-Neuro-Oncology/6th Meeting of the European-Association-for-Neur-Oncology 7 :383-384 Author Url
Garnett MC, Higgins S, Hutcheon GA, Kallinteri P. 2004. Enzymatic synthesis of novel functionalised polyesters and their use as a biodegradable nanoparticle drug delivery system JOURNAL OF PHARMACY AND PHARMACOLOGY, 56 :S49-S50 Author Url
Moore BD, Hutcheon GA, Koechlin A. 1998. Probing enzyme active sites in organic solvents using electrospray ionisation mass spectrometry. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 216 :U255-U255 Author Url
Saleem IY, Hutcheon GA, Satyanarayana S. Pulmonary Delivery of Beclometasone Loaded PGA-co-PDL Nanocomposite Microparticles Journal of Aerosol Medicine and Pulmonary Drug Delivery, Drug Delivery to the Lungs Author Url
Saleem I, Kunda NK, Somavarapu S, Gordon SB, Hutcheon GA. Protein Adsorbed PGA-co-PDL Nanocarriers for Vaccine Delivery Saleem IY. AAPS Annual Meeting and Exposition
Saleem I, Kunda NK, Somavarapu S, Gordon SB, Hutcheon GA. Protein Adsorbed PGA-co-PDL Nanocarriers for Vaccine Delivery Saleem IY. AAPS Annual Meeting and Exposition
Seton L, Kumar D, Roberts M, Patel S, Pritchard R, Bradshaw IJ, Hutcheon GA. Solid state characterisation of a highly polymorphic system to explain differences in tabletting and dissolution properties 10th International Symposium on the Crystal Growth of Organic Materials
Hamilton AR, Roberts M, Hutcheon GA, Gaskell EE. Utilising montmorillonite K-10 and Laponite for delivery of ciprofloxacin UK & Ireland Controlled Release Society
alfagih I, Alanazi FK, kunda N, hutcheon G, saleem I. Protein loaded nancomposite microparticles for inhalation Journal of Aerosol Medicine and Pulmonary Drug Delivery, 26 DOI
Valeria C, Ayca P, Gillian H, Saleem I, Adel M. Dry powder intended for pulmonary delivery: Comparison between PGA-co-PDL and chitosan Nano Composite Microparticles Journal of Aerosol Medicine and Pulmonary Drug Delivery, Author Url
Alfagih I, Kunda N, Alanazi F, Hutcheon G, Saleem I. CATIONIC PGA-CO-PDL NANOCOMPOSITE MICROPARTICLES FOR ANTIGEN DELIVERY VIA INHALATION Journal of Aerosol Medicine and Pulmonary Drug Delivery,
Tawfeek H, Khidr S, Samy E, Ahmed S, Shabir A, Mohammed A, Hutcheon G, Saleem I. pulmonary delivery of α-chymotrypsin via novel polyester microparticles Journal of Pharmacy and Pharmacology, 62
Poster
Mohamed A, Ross K, Saleem IY, Hutcheon GA. 2016. Pulmonary Delivery of Therapeutic miR-146a Nanoparticles. AAPS National Biotechnology Conference, Boston, USA.
Mohamed A, Ross K, Saleem IY, Hutcheon GA. 2015. Polymeric Nanoparticles for the Pulmonary Delivery of miRNA to Treat Chronic Obstructive Pulmonary Disease (COPD). 42nd Annual Meeting & Exposition of the Controlled Release Society, Edinburgh.
Research Grants Awarded:
Liverpool John Moores University (PhD studentship), Synthesis and formulation of anti-migraine peptides for nose-to-brain delivery, Prof. Gillian Hutcheon (lead supervisor), Dr Amos Fatokun (co-supervisor), Dr Chris Coxon (co-supervisor), Prof. Dave Kendall (co-supervisor), Grant value (£): 62,000, Duration of research project: 3 years. 2018
Innovate UK Biomedical Catalyst, Development of small peptide CGRP antagonists for migraine therapy, Prof. Dave Kendall, PharmNovo UK, Dr Chris Coxon, LJMU, Dr Imran Saleem, LJMU, Grant value (£): £195020 (£97489 to LJMU), Duration of research project: 1 year. 2017
Erasmus Mundus Programme (externally-funded PhD studentship), Pulmonary delivery of resveratrol-loaded nanocomposite microparticles to treat lung cancer, Prof. Gillian Hutcheon (lead supervisor), Dr Amos Fatokun (co-supervisor), Prof. Satyajit Sarker (co-supervisor), Grant value (£): 80,000, Duration of research project: 4 years. 2015
Conference presentation:
Pulmonary Delivery of Therapeutic miR-146a Nanoparticles, AAPS National Biotechnology Conference, 2016, Boston, USA, Poster presentation. 2016