Dr Stefan Roesner
Pharmacy and Biomolecular Sciences
Faculty of Science
Email: S.K.Roesner@ljmu.ac.uk
Academic profile
ORCID
Stefan completed his undergraduate degree at the Philipps-University Marburg in Germany, before moving to the UK to complete a PhD with Varinder Aggarwal at the University of Bristol, focusing on enantioselective lithiation-borylation reactions. He then moved to the United States to undertake postdoctoral research with Stephen Buchwald at the Massachusetts Institute of Technology, working on palladium-catalysed cross-coupling reactions under continuous-flow conditions. Following this, Stefan returned to the UK as a Senior Research Fellow and later Assistant Professor at the University of Warwick, collaborating with Mike Shipman on peptidomimetics and small nitrogen heterocycles. In April 2024, Stefan became a Senior Lecturer at Liverpool John Moores University, where he continues his research in organometallic and heterocyclic chemistry.
Languages
English
German
Degrees
2014, University of Bristol, United Kingdom, PhD, Organic Chemistry
2010, Philipp University of Marburg, Germany, Diploma (MChem), Chemistry
Certifications
2021, University of Warwick, United Kingdom, Postgraduate award in Technology Enhanced Learning
Academic appointments
Senior Lecturer in Organic Chemistry, School of Pharmacy and Biomolecular Science, Liverpool John Moores University, 2024 - present
Assistant Professor, Department of Chemistry, University of Warwick, 2021 - 2024
Senior Research Fellow, Department of Chemistry, University of Warwick, 2016 - 2021
Postdoctoral Research Associate, Department of Chemistry, Massachusetts Institute of Technology, 2015 - 2016
Journal article
Mohanrao R, Pinto CS, Suchenko A, Clarkson GJ, Wills M, Roesner S, Shipman M, Balasubramanian MK. 2025. Single‐Benzene‐Based Clickable Fluorophores for In Vitro and In Vivo Bioimaging ChemistrySelect, 10 DOI Publisher Url
Nutter M, Stone H, Shipman M, Roesner S. 2024. Stereoselective synthesis of (R)- and (S)-1,2-diazetidine-3-carboxylic acid derivatives for peptidomimetics Organic & Biomolecular Chemistry, 22 :2974-2977 DOI Author Url Publisher Url Public Url
Saunders GJ, Spring SA, Jayawant E, Wilkening I, Roesner S, Clarkson GJ, Dixon AM, Notman R, Shipman M. 2024. Synthesis and Functionalization of Azetidine-Containing Small Macrocyclic Peptides Chemistry - A European Journal, :1-7 DOI Author Url Publisher Url Public Url
Kim J, Ren X, Zhang Y, Fazzi D, Manikandan S, Andreasen JW, Sun X, Ursel S, Un HI, Peralta S, Xiao M, Town J, Marathianos A, Roesner S, Bui TT, Ludwigs S, Sirringhaus H, Wang S. 2023. Efficient N-Type Organic Electrochemical Transistors and Field-Effect Transistors Based on PNDI-Copolymers Bearing Fluorinated Selenophene-Vinylene-Selenophenes Advanced Science, 10 :1-12 DOI Author Url Publisher Url Public Url
Clarkson GJ, Roesner S. 2022. Synthesis of Benzofuropyridines and Dibenzofurans by a Metalation/Negishi Cross-Coupling/SNAr Reaction Sequence The Journal of Organic Chemistry, 88 :684-689 DOI Author Url Publisher Url Public Url
Sathiyalingam S, Roesner S. 2022. Synthesis of α- and β-Carbolines by a Metalation/Negishi Cross- Coupling/SNAr Reaction Sequence Advanced Synthesis & Catalysis, 364 :1769-1774 DOI Publisher Url Public Url
Dean C, Roesner S, Rajkumar S, Clarkson GJ, Jones M, Shipman M. 2020. Synthesis of sp3-rich chemical libraries based upon 1,2-diazetidines Tetrahedron, 79 :1-5 DOI Publisher Url Public Url
Roesner S, Beadle JD, Tam LKB, Wilkening I, Clarkson GJ, Raubo P, Shipman M. 2020. Development of oxetane modified building blocks for peptide synthesis Organic and Biomolecular Chemistry, 18 :5400-5405 DOI Author Url Publisher Url Public Url
Dean C, Rajkumar S, Roesner S, Carson N, Clarkson GJ, Wills M, Jones M, Shipman M. 2020. Readily accessible sp3-rich cyclic hydrazine frameworks exploiting nitrogen fluxionality Chemical Science, 11 :1636-1642 DOI Author Url Publisher Url Public Url
Roesner S, Saunders GJ, Wilkening I, Jayawant E, Geden JV, Kerby P, Dixon AM, Notman R, Shipman M. 2019. Macrocyclisation of small peptides enabled by oxetane incorporation Chemical Science, 10 :2465-2472 DOI Author Url Publisher Url Public Url
Noble A, Roesner S, Aggarwal VK. 2016. Short Enantioselective Total Synthesis of Tatanan A and 3-epi-Tatanan A Using Assembly-Line Synthesis Angewandte Chemie - International Edition, 55 :15920-15924 DOI Author Url Publisher Url Public Url
Noble A, Roesner S, Aggarwal VK. 2016. Short Enantioselective Total Synthesis of Tatanan A and 3‐epi‐Tatanan A Using Assembly‐Line Synthesis Angewandte Chemie, 128 :16152-16156 DOI Publisher Url
Roesner S, Buchwald SL. 2016. Continuous-Flow Synthesis of Biaryls by Negishi Cross-Coupling of Fluoro- and Trifluoromethyl-Substituted (Hetero)arenes Angewandte Chemie - International Edition, 55 :10463-10467 DOI Author Url Publisher Url Public Url
Roesner S, Buchwald SL. 2016. Continuous‐Flow Synthesis of Biaryls by Negishi Cross‐Coupling of Fluoro‐ and Trifluoromethyl‐Substituted (Hetero)arenes Angewandte Chemie, 128 :10619-10623 DOI Publisher Url
Roesner S, Blair DJ, Aggarwal VK. 2015. Enantioselective installation of adjacent tertiary benzylic stereocentres using lithiation-borylation-protodeboronation methodology. Application to the synthesis of bifluranol and fluorohexestrol Chemical Science, 6 :3718-3723 DOI Author Url Publisher Url
Roesner S, Brown CA, Mohiti M, Pulis AP, Rasappan R, Blair DJ, Essafi S, Leonori D, Aggarwal VK. 2014. ChemInform Abstract: Stereospecific Conversion of Alcohols into Pinacol Boronic Esters Using Lithiation—Borylation Methodology with Pinacolborane. ChemInform, 45 DOI Publisher Url
Roesner S, Brown CA, Mohiti M, Pulis AP, Rasappan R, Blair DJ, Essafi S, Leonori D, Aggarwal VK. 2014. Stereospecific conversion of alcohols into pinacol boronic esters using lithiation-borylation methodology with pinacolborane Chemical Communications, 50 :4053-4055 DOI Author Url Publisher Url
Roesner S, Aggarwal VK. 2012. Enantioselective synthesis of (R)-tolterodine using lithiation/borylation- protodeboronation methodology Canadian Journal of Chemistry, 90 :965-974 DOI Author Url Publisher Url
Roesner S, Aggarwal VK. 2012. Organic chemistry: Reactions at the end of a tether Nature, 487 :48-49 DOI Author Url Publisher Url
Roesner S, Casatejada JM, Elford TG, Sonawane RP, Aggarwal VK. 2011. Enantioselective syntheses of (+)-sertraline and (+)-indatraline using lithiation/borylation-protodeboronation methodology Organic Letters, 13 :5740-5743 DOI Author Url Publisher Url
Hilt G, Roesner S. 2011. ChemInform Abstract: Substrate‐Controlled Regioselective Cobalt(I)‐Catalyzed 1,4‐Hydrovinylation Reactions. ChemInform, 42 DOI Publisher Url
Kersten L, Roesner S, Hilt G. 2011. ChemInform Abstract: Synthesis and Characterization of Polycarbonyl Compounds via Their BF2‐Adducts. ChemInform, 42 DOI Publisher Url
Hilt G, Roesner S. 2011. Substrate-controlled regioselective cobalt(I)-catalysed 1,4-hydrovinylation reactions Synthesis, :662-668 DOI Publisher Url
Kersten L, Roesner S, Hilt G. 2010. Synthesis and characterization of polycarbonyl compounds via their BF
preprint
Mohanrao R, Pinto CS, Suchenko A, Clarkson GJ, Wills M, Roesner S, Shipman M, Balasubramanian MK. 2024. Single-benzene-based clickable fluorophores for in vitro and in vivo bioimaging American Chemical Society (ACS) DOI Publisher Url
Clarkson GJ, Roesner S. 2022. Synthesis of Benzofuropyridines and Dibenzofurans by a Metalation/Negishi Cross-Coupling/SNAr Reaction Sequence American Chemical Society (ACS) DOI Publisher Url
Sathiyalingam S, Roesner S. 2021. Synthesis of α- and β-Carbolines by a Metalation/Negishi Cross-Coupling/SNAr Reaction Sequence American Chemical Society (ACS) DOI Publisher Url
Sathiyalingam S, Roesner S. 2021. Synthesis of α- and β-Carbolines by a Metalation/Negishi Cross-Coupling/SNAr Reaction Sequence Cambridge University Press (CUP) DOI Publisher Url
Roesner S, Sathiyalingam S. 2021. Synthesis of α- and β-Carbolines by a Metalation/Negishi Cross-Coupling/SNAr Reaction Sequence Cambridge University Press (CUP) DOI Publisher Url
Roesner S, Sathiyalingam S. 2021. Synthesis of α- and β-Carbolines by a Metalation/Negishi Cross-Coupling/SNAr Reaction Sequence American Chemical Society (ACS) DOI Publisher Url
Chapters
Boswood S, Roesner S. 2024. Methodologies for the synthesis of β-carbolines Targets in heterocyclic systems 27 :1-22 Italian Chemical Society DOI Publisher Url Public Url
Conference publication
Roesner S. 2018. Macrocyclization of Small Peptides Enabled by Oxetane Incorporation JOURNAL OF PEPTIDE SCIENCE, 24 :S60-S60